tissue factor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4502	BISMUTH SUBGALLATE	Dermatol Puder,Bismuth Gallate	Others
	Bismuth subgallate (Dermatol Puder) is an astringent and antiseptic and is applied to skin diseases such as eczema.		Others
T35343	MTI-31	MTI-31,LXI-15029	mTOR
	MTI-31 (LXI-15029) is a potent, orally active and highly selective inhibitor of mTORC1 and mTORC2. MTI-31 is selective for mTOR (Kd: 0.20 nM) versus PIK3CA, PIK3CB and PIK3G with >5,000 fold selectivity in mTOR binding a...		mTOR
T2S0504	Ilexoside D		Others
	Ilexoside D has ant-allergic, and anti-coagulant activities, it shows anti-tissue factor activity as well as the antithrombotic activity.		Others
T77372	Tisotumab	1E10,1.00E+10	Others
	Tisotumab (Anti-Human F3 Recombinant Antibody) is a human IgG1 monoclonal antibody against tissue factor (TF). Tisotumab is involved in antibody-conjugating drugs that can be used to study cancer.		Others
T76761	Olaratumab	LY3012207,IMC-3G3	PDGFR
	Olaratumab(IMC-3G3) is a human monoclonal IgG1 antibody against platelet-derived growth factor receptor alpha (PDGFRα), which has antitumor effects and can be used to study advanced soft tissue sarcomas.		PDGFR
T15577	Indobufen	Ibustrin	COX
	Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue fac...		COX
T21632	Myoseverin		Others , Microtubule Associated
	Myoseverin, an inducer of the reversible fission of multinucleated myotubes into mononucleated fragments, affecting the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and str...		Others , Microtubule Associated
T3469	PCI-27483	PCI27483	Others
	PCI-27483 is an activated coagulation factor VIIa inhibitor with antithrombotic effects in a baboon model of arterial thrombosis. It also inhibits the growth of BxPC3 xenografts by 42% and 85% at doses of 60 and 90 mg/kg...		Others
T2S2264	Linalool	Linalol,(±)-Linalool,Phantol	Apoptosis , IL Receptor , TNF , Endogenous Metabolite , iGluR
	1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury th...
T28222	5-Hydroxy-1-methylhydantoin	HD-003,HD003,NZ419,NZ-419,HD 003,NZ 419	Bradykinin Receptor
	5-Hydroxy-1-methylhydantoin (HD-003) is an antioxidant potentially for the treatment of renal failure. A creatinine metabolite, 5-Hydroxy-1-methylhydantoin , a hydroxyl radical scavenger, has previously been shown to con...		Bradykinin Receptor
T29501	A 68828	A68828,A-68828
	A 68828 is an analog of the atrial natrium factor. It improves kidney function and reduces tissue damage.
T69456	Melagatran monohydrate
	Melagatran monohydrate is a thrombin inhibitor. Melagatran prevents tissue factor expression in human platelet-monocyte heterotypic complexes. Melagatran reduces advanced atherosclerotic lesion size and may promote plaqu...
T81854	Marstacimab	PF-06741086
	Marstacimab (PF-06741086), an anti-tissue factor pathway inhibitor (TFPI) monoclonal antibody, is utilized in hemophilia research [1] [2].
T41139	Echinocystic acid 28-O-β-D-glucoside
	Echinocystic acid 28-O-β-D-glucoside is a metabolite resulting from the microbial oxidation and glucosidation of Echinocystic acid. It exhibits inhibitory activity towards the tissue factor pathway, with an IC50 value me...
T76804	FG-3019
	Pamrevlumab (FG-3019) is a recombinant human antibody targeting connective tissue growth factor (CTGF), with potential applications in idiopathic pulmonary fibrosis (IPF) research [1] [2].
T76921	Befovacimab
	Befovacimab (BAY 1093884), a fully human monoclonal IgG2 antibody, binds to the tissue factor pathway inhibitor (TFPI). It is utilized in research for haemophilia A/B [1].
T75152	ARC19499
	ARC19499, an aptamer, inhibits the tissue factor pathway inhibitor (TFPI), facilitating clot initiation and propagation through the extrinsic pathway. It binds specifically to TFPI, blocking its inhibition of both factor...
T77881	Tisotumab vedotin
	Tisotumab vedotin is an antibody-drug conjugate (ADC) that specifically targets tissue factor (TF). This compound combines a fully human monoclonal antibody directed against TF (TF-011) with the cytotoxic agent Monomethy...
T68302	KD3010 tosylate
	KD-3010 is a peroxisome proliferator-activated receptor delta agonist potentially for the treatment of diabetes and obesity. KD-3010 dramatically ameliorates liver injury induced by carbon tetrachloride (CCl(4)) injecti...
TMIH-0281	Indobufen-d5
	Indobufen-d5 is a deuterated compound of Indobufen. Indobufen has a CAS number of 63610-08-2. Indobufen is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobu...